The two members of the pair of alleles segregate or separate into two diverse gametes and exert their impact in an offspring as one of a novel pair of alleles. Conclusion to a critical analysis essay.
When united with a gamete from the other parent during fertilization and conception, the resulting offspring has 46 chromosomes.
People with Down syndrome also have white spots on the iris.
Down syndrome’s indicators range from mild to severe. Down syndrome is a genetic disorder that occurs as a result of an additional chromosome. Josh Richardson A risk of 1 per cent also exists for parents who have conceived a child having Down syndrome. In conclusion, Down syndrome is a genetic disorder caused by an additional twenty first chromosome. During meiosis, chromosomes are required to divide and go to diverse regions of the cell, a meiotic step known as disjunction. There are other distinguishable appearance for those who have trisomy 21 but these are the most, A Comparison Of Their Eyes Were Watching God And Of Mice And Men, Environmental Impacts: The Impact Of Genetically Modified Foods, Literary Analysis: The Neckless By Mme Loisel, Human Psychology In The Cask Of Amontillado.
Individuals with Down syndrome also suffer from leukemia, Alzheimer’s disease, heart defects and gastrointestinal problems. The effects of the disorder on physical and mental development are severe and are expressed throughout the life span.
When the Normal 14 and normal 21 is united with a typical gamete from the other parent, it results to a normal offspring, while a translocated 14/21 results to an offspring with translocation Down syndrome. Errors taking place during mitosis or meiosis can result to chromosomal aberrations where large portions of chromosomes or whole chromosomes are added or missing.
When the normal 14 only is united with a normal gamete from the other parent it becomes lethal and leads to spontaneous abortion. The characteristics of Down syndrome are linked to genes present in the additional copy of chromosome 21. Chromosomes in cells are made up of proteins and genetic information in form of DNA. Instead of chromosome 21 separating and moving to opposite regions of the cell during meiosis, they fail to detach resulting to disjunction which makes the reproductive cell to have abnormal number of chromosomes. In prokaryotic cell there isn’t a nucleus and the DNA is free within the cytoplasm. Chromosome segregation is the coordinated movement of chromosomes to the opposite poles of cell during cellular reproduction or mitosis of during production of sex cells or meiosis.
In Down syndrome, the egg gains an additional copy of chromosome 21, and when it unites with a normal sperm, the resulting child has three copies of chromosome 21. The disorder affects 1 of 800 live births and the dominating causative factor for cognitive impairment.
This type is the most common out of the three, accounting for 95% of the cases.
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